Endocrine Abstracts

Introduction: Turner syndrome (TS) is a chromosomal disorder affecting female and characterized by complete or partial monosomy of the X chromosome. These genetic changes lead to the abnormalities in growth and development and increase the risk of autoimmune diseases, including those affecting the thyroid. Thyroid pathology in TS may include autoimmune thyroiditis, hypothyroidism, thyrotoxicosis (Graves disease, AIT in the hyperthyroid state). Thyrotoxicosis is the clinical sy...

Background: ACTH-ectopic syndrome is a rare cause of endogenous hypercortisolism and may pose serious difficulties in topical diagnosis.Case description: Clinical features of hypercortisolism manifested at the age of 18 years (2012). A year later he was referred to an endocrinologist: ACTH 113 pg/ml (0–46), cortisol in 24-h urine 2915 μg/day (4.3–176), 1 mg DX test cortisol 1020 nmol/l, 8 mg DX test 764 nmol/l, intact pituitary MRI with co...

Aim/introduction: The main purpose of this work was to describe a clinical case of thyrotoxicosis with concomitant HASHARON hemoglobinopathy scrutinizing whether the latter could hinder radioiodine therapy (RIT).Materials and methods: Patient H., 53 years old, diagnosed with moderate toxic diffuse multinodular goiter. Clinical manifestation of the disease were in summer 2018 (TSH – 0 mIU/ml). Medication with thyrozole (20 mg) was initiated. Thyroto...